Anticoagulation and Stroke Prevention

Updated Clinical Practice Guideline: Pharmacologic Management of Newly Detected Atrial Fibrillation (Frost et al, 2017)

Guidelines/Clinical Documents: To review the evidence and provide clinical recommendations for the pharmacologic management of atrial fibrillation. Methods: This guideline is based on two systematic reviews of published randomized controlled trials (RCTs) and prospective and retrospective observational studies from 2000 to 2012. An updated literature search was performed to identify new studies from 2012 to December 31, 2015. The targeted audience for the guideline includes all primary care clinicians, and the targeted patient population includes adults who have nonvalvular atrial fibrillation that is not due to a reversible cause. This guideline was developed using a modified version of GRADE to evaluate the quality of the evidence and make recommendations based on the balance of benefits and harms.

Guidelines for the Primary Prevention of Stroke: A Statement for Healthcare Professionals From the AHA/ASA

Guidelines/Clinical Documents: Guidelines document outlining best practices for the primary prevention of stroke among individuals who have not previously experienced a stroke or transient ischemic attack.

Antithrombotic Therapy for Atrial Fibrillation: CHEST Guideline and Expert Panel Report (Lip et al, Chest 2018)

Guidelines/Clinical Documents: These guidelines for best practices provides recommendations for antithrombotic treatment based on net clinical benefit for patients with AF at varying levels of stroke risk and in a number of common clinical scenarios.

2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation

Guidelines/Clinical Documents: 2021 Position paper from the European Heart Rhythm Association to serve as a guide for providers when using Non-Vitamin K Antagonist OACs in AFib patients. Published on behalf of the European Society of Cardiology.

Management of Anticoagulation in the Peri-Procedural Period (MAPPP) App: Overview, Instructions and Case Studies

Meta-Analyses/Systematic Review of Literature: Extensive PowerPoint presentation on the management of anticoagulation in the peri-procedural period. Includes overview, instructions, and case studies.

Rationale, considerations, and goals for atrial fibrillation centers of excellence: A Heart Rhythm Society perspective

Guidelines/Clinical Documents: This manuscript builds on the work of a diverse, multiple-stakeholder Think Tank meeting and multidisciplinary Inter-pro Forum educational activity held in January 2019, both led by the Heart Rhythm Society (HRS). When examining the current clinical landscape, the Think Tank concluded that there is a clear need for AF CoEs to improve AF care and its delivery. In this manuscript, HRS hopes to accelerate this evolution by reviewing the rationale for AF CoEs, the available evidence for integrated and multidisciplinary care, and future challenges and opportunities. The document also defines the key priorities to be used as a guide for HRS and its diverse stakeholders to build consensus on defining the core components of an AF CoE.