Journal Articles

2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation

Guidelines/Clinical Documents: 2021 Position paper from the European Heart Rhythm Association to serve as a guide for providers when using Non-Vitamin K Antagonist OACs in AFib patients. Published on behalf of the European Society of Cardiology.

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Early Rhythm-Control Therapy in Patients with Atrial Fibrillation

Journal Articles: In this international, investigator-initiated, parallel-group, open, blinded-outcome assessment trial, we randomly assigned patients who had early atrial fibrillation (diagnosed ≤1 year before enrollment) and cardiovascular conditions to receive either early rhythm control or usual care. Early rhythm control included treatment with antiarrhythmic drugs or atrial fibrillation ablation after randomization. Usual care limited rhythm control to the management of atrial fibrillation–related symptoms. The first primary outcome was a composite of death from cardiovascular causes, stroke, or hospitalization with worsening of heart failure or acute coronary syndrome; the second primary outcome was the number of nights spent in the hospital per year. The primary safety outcome was a composite of death, stroke, or serious adverse events related to rhythm-control therapy. Secondary outcomes, including symptoms and left ventricular function, were also evaluated.

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Biomedical Imaging and Intervention Journal

Care Pathways/CDS: This article describes the results of a transition-of-care protocol that was developed to improve guideline-based oral anticoagulant management in the emergency department of a medical center located in an under-served San Diego community. This article also describes treatment gaps in prescribing oral anticoagulants for patients with non-valvular atrial fibrillation at risk for stroke in the emergency department.

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